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Лекарственный препарат Кандитрал

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            [WF_LOCKED_BY] => 
            [WF_DATE_LOCK] => 
            [WF_COMMENTS] => 
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            [SHOW_COUNTER] => 
            [SHOW_COUNTER_START] => 
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            [CODE] => 
            [TAGS] => 
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            [TMP_ID] => 9a14b78125ae1d5a8cfdcd61a2f573ed
            [USER_NAME] => (Midnik) Ivan VIS
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            [IBLOCK_NAME] => Торговые предложения
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            [CANONICAL_PAGE_URL] => 
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                            [USER_TYPE_SETTINGS] => 
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                    [STARTSHOP_PRICE_1] => Array
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                            [USER_TYPE_SETTINGS] => 
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                            [SORT] => 500
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                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
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                            [IBLOCK_ID] => 26
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                            [SORT] => 500
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
                            [MULTIPLE] => N
                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
                            [WITH_DESCRIPTION] => N
                            [SEARCHABLE] => N
                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => directory
                            [USER_TYPE_SETTINGS] => Array
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                                    [width] => 0
                                    [group] => N
                                    [multiple] => N
                                    [TABLE_NAME] => universe_colors
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                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
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                    [SIZE] => Array
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                            [XML_ID] => 
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
                            [WITH_DESCRIPTION] => N
                            [SEARCHABLE] => N
                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
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                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
                            [VALUE_ENUM_ID] => 
                            [~VALUE] => 
                            [~DESCRIPTION] => 
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                            [~DEFAULT_VALUE] => 
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                    [STARTSHOP_LINK] => Array
                        (
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                            [XML_ID] => 
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                            [USER_TYPE] => 
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                    [NAME] => Array
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
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                            [SEARCHABLE] => N
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                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
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                        )

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                            [NAME] => URL
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                            [SORT] => 500
                            [CODE] => URL
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
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                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
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                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
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                        )

                    [DATA] => Array
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                            [XML_ID] => 
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                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
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                            [TIMESTAMP_X] => 2019-10-14 16:10:42
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                            [NAME] => Партнерская ссылка
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                            [SORT] => 500
                            [CODE] => PARTNER_URL
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                            [COL_COUNT] => 30
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                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
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                            [SEARCHABLE] => N
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                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
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                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
                            [~VALUE] => 
                            [~DESCRIPTION] => 
                            [~NAME] => Партнерская ссылка
                            [~DEFAULT_VALUE] => 
                            [VALUE_ENUM_ID] => 
                        )

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                        (
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                            [TIMESTAMP_X] => 2019-10-14 19:00:11
                            [IBLOCK_ID] => 26
                            [NAME] => ID лекарства в партнерке
                            [ACTIVE] => Y
                            [SORT] => 500
                            [CODE] => ID_PARTNER_LEK
                            [DEFAULT_VALUE] => 
                            [PROPERTY_TYPE] => S
                            [ROW_COUNT] => 1
                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
                            [MULTIPLE] => N
                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
                            [WITH_DESCRIPTION] => N
                            [SEARCHABLE] => N
                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
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                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
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                            [~DESCRIPTION] => 
                            [~NAME] => ID лекарства в партнерке
                            [~DEFAULT_VALUE] => 
                            [VALUE_ENUM_ID] => 
                        )

                )

            [STARTSHOP] => Array
                (
                    [PRICES] => Array
                        (
                            [LIST] => Array
                                (
                                    [BASE] => Array
                                        (
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                                            [CURRENCY] => RUB
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                                            [TYPE] => BASE
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                                )

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                                (
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                                    [CURRENCY] => RUB
                                    [PRINT_VALUE] => 1 269 руб.
                                    [TYPE] => BASE
                                )

                        )

                    [BASKET] => Array
                        (
                            [INSIDE] => 
                            [QUANTITY] => 0
                            [PRICE] => Array
                                (
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                                    [CURRENCY] => RUB
                                    [PRINT_VALUE] => 1 269 руб.
                                    [TYPE] => BASE
                                )

                        )

                    [QUANTITY] => Array
                        (
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                            [RATIO] => 1
                            [VALUE] => 100
                        )

                    [AVAILABLE] => 1
                    [OFFER] => Array
                        (
                            [OFFER] => 1
                            [PROPERTIES] => Array
                                (
                                )

                            [LINK] => 10745
                        )

                )

            [PRICE] => Array
                (
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                    [CURRENCY] => RUB
                    [PRINT_VALUE] => 1 269 руб.
                    [TYPE] => BASE
                    [DISCOUNT_VALUE] => 1 269 руб.
                    [PRINT_DISCOUNT_VALUE] => 1 269 руб.
                    [DISCOUNT_DIFF] => 0
                    [DISCOUNT_DIFF_PERCENT] => 0
                )

            [CATALOG_QUANTITY] => 100
            [MAX_QUANTITY] => 100
            [CATALOG_MEASURE_RATIO] => 1
            [MEASURE] => 
            [CAN_BUY] => 1
            [CAN_BUY_ZERO] => 
        )

)
Рецептурный препарат Рецептурный препарат. Рецепт остается в аптеке

Инструкция по применению Кандитрал

Производитель

Гленмарк Фармасьютикалз Лтд

Страна происхождения

Индия

Группа товаров

Противогрибковые препараты

Противогрибковый препарат

Формы выпуска

  • 7 - упаковки ячейковые контурные (2) - пачки картонные.

Описание лекарственной формы

  • Капсулы

Фармакологическое действие

Синтетическое противогрибковое средство широкого спектра действия. Производное триазола. Подавляет синтез эргостерола клеточной мембраны грибов. Активен в отношении дерматофитов (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), дрожжевых грибов Candida spp. (включая Candida albicans, Candida parapsilosis), плесневых грибов (Cryptococcus neoformans, Aspergillus spp., Trichosporon spp., Geotrichum spp., Penicillium marneffei, Pseudallescheria boydii, Histoplasma spp., Coccidioides immitis, Paracoccidioides braziliensis, Sporothrix schenckii, Fonsecaea spp., Cladosporium spp., Blastomyces dermatidis), Malassezia spp. Некоторые штаммы могут быть устойчивы: Candida glabrata, Candida krusei, Candida tropicalis, Absidia spp., Fusarium spp., Mucor spp., Rhizomucor spp., Rhizopus spp., Scedosporium proliferans, Scopulariopsis spp. Эффективность лечения оценивается через 2-4 нед после прекращения терапии (при микозах), через 6-9 мес - при онихомикозах (по мере смены ногтей).

Особые условия

Для предотвращения реинфекции необходимо одновременное лечение половых партнеров и соблюдение личной гигиены. В период лечения рекомендуется воздерживаться от половых контактов. При сохранении признаков инфекции после завершения лечения, следует провести повторное микробиологическое исследование с целью подтверждения диагноза. Эффективность итраконазола для лечения грибковых инфекций при тяжелой нейтропении неизвестна, поэтому в таких случаях препарат должен использоваться только при неэффективности 1-й линии терапии. При возникновении факторов риска ХСН (ИБС, поражение сердечных клапанов, тяжелые заболевания легких, в т.ч. ХОБЛ, состояния, сопровождающиеся отечным синдромом) во время лечения итраконазолом терапию следует отменить. При приеме итраконазола у некоторых пациентов отмечалась преходящая и постоянная глухота. Раствор итраконазола для приема внутрь содержит собритол, что следует учитывать у больных с врожденной непереносимостью фруктозы.

Состав

  • итраконазол в форме пеллет470 мг, что соответствует содержанию итраконазола100 мг Вспомогательные вещества: гипромеллоза (гидроксипропилметилцеллюлоза Е5), эудрагит Е-100 (сополимер метилметакрилата, диметиламиноэтилметакрилата и бутилметакрилата), сахароза. Состав капсулы: желатин, вода очищенная, метилпарагидроксибензоат, пропилпарагидроксибензоат, натрия лаурилсульфат. Красители крышечки капсулы: титана диоксид, железа оксид черный (для нанесения логотипа фирмы "G"). Красители корпуса капсулы: краситель пунцовый (Понсо 4R), азорубин (кармоизин), титана диоксид (для надписи "canditral").

Кандитрал показания к применению

  • — дерматомикозы; — грибковый кератит; — онихомикозы, вызванные дерматофитами и/или дрожжами и плесневыми грибами; — системные микозы: — системный аспергиллез и кандидоз; — криптококкоз, включая криптококковый менингит (пациентам с иммунодефицитом и пациентам с криптококкозом центральной нервной системы Кандитрал должен назначаться только в случаях, если препараты первой линии лечения не применимы в данном случае или не эффективны); — гистоплазмоз; — споротризоз; — паракокцидиоидомикоз; — бластомикоз; — другие системные или тропические микозы; — кандидомикозы с поражением кожи и слизистых, в том числе вульвовагинальный кандидоз; — глубокие висцеральные кандидозы; — отрубевидный лишай.

Кандитрал противопоказания

  • — индивидуальная повышенная чувствительность к препарату или его компонентам; — одновременный с препаратом Кандитрал прием следующих лекарственных средств: — препараты, метаболизируемые ферментом CYP3A4, которые могут увеличивать QT интервал (терфенадин, астемизол, мизоластин, цизаприд, дофетилид, хинидин, пимозид, левометадон, сертиндол); — ингибиторы редуктазы ГМГ-КоА, расщепляемые ферментом CYP3A4 (симвастатин, ловастатин); — мидазолам и триазолам (для приема внутрь); — препараты алкалоидов спорыньи (дигидроэрготамин, эргометрин, эрготамин и метилэргометрин); — детский возраст до 3-х лет. С осторожностью: детский возраст, тяжелая сердечная недостаточность, заболевания печени (в том числе сопровождающиеся печеночной недостаточностью), хроническая почечная недостаточность

Кандитрал дозировка

  • 100 мг

Кандитрал побочные действия

  • Со стороны желудочно-кишечного тракта: диспепсия, тошнота, рвота, снижение аппетита, боль в животе, диарея, запор. Со стороны гепато-билиарной системы: обратимое повышение активности «печеночных» трансаминаз, гепатит; очень редко – тяжелое токсическое поражение печени, в том числе острая печеночная недостаточность с летальным исходом. Со стороны нервной системы: головная боль, головокружение, периферическая нейропатия. Аллергические реакции: кожная сыпь, кожный зуд, крапивница, ангионевротический отек, редко - мультиформная экссудативная эритема (синдром Стивенса-Джонсона). Со стороны кожных покровов: алопеция, светочувствительность Прочие: нарушения менструального цикла, гипокалиемия, отечный синдром, застойная сердечная недостаточность и отек легких, гиперкреатинемия, окрашивание мочи в темный цвет.

Лекарственное взаимодействие

ЛС, снижающие кислотность желудочного сока, нарушают абсорбцию итраконазола (капсулы). Индукторы изофермента CYP3A4 (в т.ч. рифампицин, рифабутин, фенитоин) снижают биодоступность итраконазола, а ингибиторы изофермента CYP3A4 (в т.ч. ритонавир, индинавир, кларитромицин, эритромицин) повышают ее. Итраконазол усиливает действие (в т.ч. побочное) ЛС, метаболизирующихся изоферментом CYP3A4. Особую осторожность следует соблюдать при одновременном приеме непрямых антикоагулянтов, ингибиторов протеазы ВИЧ, некоторых противоопухолевых ЛС (бусульфан, доцетаксел, триметрексат, алкалоиды барвинка), БМКК, метаболизирующихся изоферментом CYP3A4 (дигидропиридины, верапамил), некоторых иммунодепрессантов (циклоспорин, такролимус, сиролимус), некоторых ГКС (будесонид, дексаметазон, флутиказон, метилпреднизолон), дигоксина (за счет ингибирования P-гликопротеина), прочих (цилостазол, дизопирамид, карбамазепин, буспирон, алфентанил, алпразолам, бротизолам, мидазолам (в/в), рифабутин, эбастин, репаглинид,

Условия хранения

  • хранить при комнатной температуре 15-25 градусов
  • беречь от детей
Отзывы Кандитрал
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