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Лекарственный препарат Магнистад

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            [WF_LOCKED_BY] => 
            [WF_DATE_LOCK] => 
            [WF_COMMENTS] => 
            [IN_SECTIONS] => N
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            [SHOW_COUNTER_START] => 
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            [CODE] => 
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                            [SORT] => 500
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                            [IBLOCK_ID] => 26
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                            [SORT] => 500
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
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                            [XML_ID] => 
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                            [TMP_ID] => 
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                            [SEARCHABLE] => N
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                            [USER_TYPE_SETTINGS] => Array
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                            [SEARCHABLE] => N
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                            [HINT] => 
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                    [STARTSHOP_LINK] => Array
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                            [SORT] => 500
                            [CODE] => NAME
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
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                            [TMP_ID] => 
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                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
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                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
                            [VALUE_ENUM_ID] => 
                            [~VALUE] => 
                            [~DESCRIPTION] => 
                            [~NAME] => Название 2
                            [~DEFAULT_VALUE] => 
                        )

                    [URL] => Array
                        (
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                            [TIMESTAMP_X] => 2019-01-30 19:09:51
                            [IBLOCK_ID] => 26
                            [NAME] => URL
                            [ACTIVE] => Y
                            [SORT] => 500
                            [CODE] => URL
                            [DEFAULT_VALUE] => 
                            [PROPERTY_TYPE] => S
                            [ROW_COUNT] => 1
                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
                            [MULTIPLE] => N
                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
                            [WITH_DESCRIPTION] => N
                            [SEARCHABLE] => N
                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
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                            [DESCRIPTION] => 
                            [VALUE_ENUM] => 
                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
                            [~VALUE] => https://www.aptekaonline.ru/lekarstva/zabolevaniya_zheludochno_kishechnye/antatsidy/magnistad_48mg5mg_n50_tab_pokrytye_kishechnorastvorimoy_obolochkoy_nizhfarm.html
                            [~DESCRIPTION] => 
                            [~NAME] => URL
                            [~DEFAULT_VALUE] => 
                            [VALUE_ENUM_ID] => 
                        )

                    [DATA] => Array
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                            [IBLOCK_ID] => 26
                            [NAME] => Дата
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                            [SORT] => 500
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                            [XML_ID] => 
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                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
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                    [PHARMACIES] => Array
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                            [TIMESTAMP_X] => 2019-08-12 14:53:52
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                            [NAME] => Аптеки
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                            [SORT] => 500
                            [CODE] => PHARMACIES
                            [DEFAULT_VALUE] => 
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
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                            [USER_TYPE] => 
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                            [HINT] => 
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                            [~DESCRIPTION] => 
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                    [PARTNER_URL] => Array
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                            [TIMESTAMP_X] => 2019-10-14 16:10:42
                            [IBLOCK_ID] => 26
                            [NAME] => Партнерская ссылка
                            [ACTIVE] => Y
                            [SORT] => 500
                            [CODE] => PARTNER_URL
                            [DEFAULT_VALUE] => 
                            [PROPERTY_TYPE] => S
                            [ROW_COUNT] => 1
                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
                            [MULTIPLE] => N
                            [XML_ID] => 
                            [FILE_TYPE] => 
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                            [TMP_ID] => 
                            [LINK_IBLOCK_ID] => 0
                            [WITH_DESCRIPTION] => N
                            [SEARCHABLE] => N
                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
                            [VALUE_ENUM] => 
                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
                            [~VALUE] => 
                            [~DESCRIPTION] => 
                            [~NAME] => Партнерская ссылка
                            [~DEFAULT_VALUE] => 
                            [VALUE_ENUM_ID] => 
                        )

                    [ID_PARTNER_LEK] => Array
                        (
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                            [TIMESTAMP_X] => 2019-10-14 19:00:11
                            [IBLOCK_ID] => 26
                            [NAME] => ID лекарства в партнерке
                            [ACTIVE] => Y
                            [SORT] => 500
                            [CODE] => ID_PARTNER_LEK
                            [DEFAULT_VALUE] => 
                            [PROPERTY_TYPE] => S
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                            [COL_COUNT] => 30
                            [LIST_TYPE] => L
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                            [XML_ID] => 
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                            [FILTRABLE] => N
                            [IS_REQUIRED] => N
                            [VERSION] => 1
                            [USER_TYPE] => 
                            [USER_TYPE_SETTINGS] => 
                            [HINT] => 
                            [PROPERTY_VALUE_ID] => 
                            [VALUE] => 
                            [DESCRIPTION] => 
                            [VALUE_ENUM] => 
                            [VALUE_XML_ID] => 
                            [VALUE_SORT] => 
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                            [~DESCRIPTION] => 
                            [~NAME] => ID лекарства в партнерке
                            [~DEFAULT_VALUE] => 
                            [VALUE_ENUM_ID] => 
                        )

                )

            [STARTSHOP] => Array
                (
                    [PRICES] => Array
                        (
                            [LIST] => Array
                                (
                                    [BASE] => Array
                                        (
                                            [VALUE] => 399
                                            [CURRENCY] => RUB
                                            [PRINT_VALUE] => 399 руб.
                                            [TYPE] => BASE
                                        )

                                )

                            [MINIMAL] => Array
                                (
                                    [VALUE] => 399
                                    [CURRENCY] => RUB
                                    [PRINT_VALUE] => 399 руб.
                                    [TYPE] => BASE
                                )

                        )

                    [BASKET] => Array
                        (
                            [INSIDE] => 
                            [QUANTITY] => 0
                            [PRICE] => Array
                                (
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                                    [CURRENCY] => RUB
                                    [PRINT_VALUE] => 399 руб.
                                    [TYPE] => BASE
                                )

                        )

                    [QUANTITY] => Array
                        (
                            [USE] => 1
                            [RATIO] => 1
                            [VALUE] => 100
                        )

                    [AVAILABLE] => 1
                    [OFFER] => Array
                        (
                            [OFFER] => 1
                            [PROPERTIES] => Array
                                (
                                )

                            [LINK] => 11010
                        )

                )

            [PRICE] => Array
                (
                    [VALUE] => 399
                    [CURRENCY] => RUB
                    [PRINT_VALUE] => 399 руб.
                    [TYPE] => BASE
                    [DISCOUNT_VALUE] => 399 руб.
                    [PRINT_DISCOUNT_VALUE] => 399 руб.
                    [DISCOUNT_DIFF] => 0
                    [DISCOUNT_DIFF_PERCENT] => 0
                )

            [CATALOG_QUANTITY] => 100
            [MAX_QUANTITY] => 100
            [CATALOG_MEASURE_RATIO] => 1
            [MEASURE] => 
            [CAN_BUY] => 1
            [CAN_BUY_ZERO] => 
        )

)

Инструкция по применению Магнистад

Производитель

ШТАДА-Вьетнам Джойнт Вентче Ко., Лтд/ уп. "Скопинс

Страна происхождения

Вьетнам/Россия

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Нервная система

Препарат, восполняющий дефицит магния в организме

Формы выпуска

  • 10 - упаковки ячейковые контурные (алюминий/ПВХ) (5) - пачки картонные.

Описание лекарственной формы

  • Таблетки овальные, двояковыпуклые, покрытые кишечнорастворимой оболочкой белого цвета

Фармакологическое действие

Комбинированный препарат; содержит лечебные дозы магния лактата и пиридоксина гидрохлорида, улучшающего всасывание магния в кишечнике, его транспорт из крови и межклеточной жидкости внутрь клеток. Магний является жизненно важным элементом, который обеспечивает поступление продуктов гликолиза в цикл Кребса, участвует в синтезе и распаде нуклеиновых кислот, синтезе белков, жирных кислот и липидов, в частности фосфолипидов, так же участвует в синтезе ферментов, обеспечивающих энергетические реакции (гликолизе, гидролитическом расщеплении АТФ). Магний необходим для осуществления нервно- мышечной передачи, минерализации костей, реализации эффекта паратгормона. Ионы магния являются физиологическим антагонистом ионов кальция. Магний образует участки в структуре ряда рецепторов (NMDA-, АМРА-рецепторов к ацетилхолину, норадреналину и дофамину), он необходим для нормального обмена нейромедиаторов (катехоламинов, тирозина, дофамина, норадреналина, серотонина, у-аминомасляной кислоты). Магний посредством активации тирозинкиназы способствует снижению инсулинорезистентности тканей и индуцированию инсулинзависимого усвоения глюкозы. Пиридоксина гидрохлорид (витамин Вб) в качестве коэнзима участвует в метаболических процессах, необходим для нормального функционирования центральной и периферической нервной системы. Поступая в организм, он фосфорилируется, превращается в пиридоксаль-5-фосфат, входит в состав ферментов, осуществляющих декарбоксилирование и трансаминирование аминокислот. Участвует в обмене триптофана, метионина, цистеина, глутаминовой и других аминокислот, липидном и углеводном обмене. Пиридоксин необходим для синтеза у-аминомасляной кислоты и гема.

Фармакокинетика

Абсорбция магния лактата в желудочно-кишечном тракте медленная, не более 50% от принятой внутрь дозы. Около 25 - 30% всосавшегося магния циркулирует в связанном с белками состоянии. Всосавшийся магний выводится почками, не всосавшаяся часть выводится через кишечник. Магний преодолевает плацентарный барьер; в небольшом количестве проникает в грудное молоко. Пиридоксина гидрохлорид хорошо всасывается в желудочно-кишечном тракте, далее метаболизируется в печени с образованием фармакологически активных метаболитов (пиридоксальфосфат и пиридоксаминофосфат). Концентрация пиридоксина в плазме в норме составляет 30 - 80 нг/мл. Больше всего пиридоксина содержится в печени, затем в мышцах и мозговой ткани. Общее содержание пиридоксина в организме составляет 167 мг. Пиридоксальфосфат с белками плазмы связывается на 90%. Период полувыведения - 15-20 дней. Выводится почками. Пиридоксальфосфат проникает через плаценту. Выводится при гемодиализе.

Особые условия

Магнистад не следует принимать на голодный желудок, поскольку возможно развитие диареи. При совместном применении с тетрациклинами необходимо соблюдать интервал 3 часа между приемами Магнистада и препаратом тетрациклинового ряда. При совместном применении с препаратами, содержащими фосфаты или соли кальция, необходимо соблюдать интервал 1 ч. Влияние на способность к вождению автотранспорта и управлению механизмами Не влияет.

Состав

  • таблетка, покрытая кишечнорастворимой оболочкой, содержит активные вещества: магния лактата дигидрат - 470,0 мг (соответствует 48,0 мг магния), пиридоксина гидрохлорид (витамин Вб) - 5,0 мг; вспомогательные вещества: крахмал пшеничный 40,0 мг, лактозы моногидрат 60,0 мг, целлюлоза микрокристаллическая 25,0 мг, повидон - К90 - 15,0 мг, кроскармеллоза натрия 20,0 мг, стеариновая кислота 15,0 мг, магния стеарат 15,0 мг; оболочка: метакриловой кислоты и метилметакрилата сополимер [1:1] (эудрагит L 100) - 22,500 мг, триэтилцитрат 4,500 мг, тальк 7,500 мг, титана диоксид 4,583 мг.

Магнистад показания к применению

  • Установленный дефицит магния, изолированный или связанный с другими дефицитными состояниями, сопровождающийся такими симптомами как: повышенная раздражительность, незначительные нарушения сна, желудочно-кишечные спазмы, учащенное сердцебиение, повышенная утомляемость, боли и спазмы мышц, ощущение покалывания

Магнистад противопоказания

  • Повышенная чувствительность к компонентам препарата, выраженная почечная недостаточность (клиренс креатинина менее 30 мл/мин), фенилкетонурия, детский возраст до 6 лет; дефицит лактазы, непереносимость лактозы, глюкозо-галактозная мальабсорбция (препарат содержит лактозу). С осторожностью Препарат следует применять с осторожностью при умеренной недостаточности функции почек, поскольку существует риск развития гипермагниемии. Беременность и период лактации Магнистад® может применяться в период беременности только по рекомендации врача. Магний проникает в грудное молоко. Следует избегать применения препарата в период лактации. При необходимости приема препарата грудное вскармливание следует прекратить.

Магнистад побочные действия

  • Аллергические реакции, боли в животе, диарея, тошнота, рвота, метеоризм

Лекарственное взаимодействие

Одновременное применение препаратов, содержащих фосфаты или соли кальция, может значительно уменьшать всасывание магния в желудочно-кишечном тракте. Препараты магния снижают всасывание тетрациклина. Магний ослабляет действие пероральных тромболитических средств, уменьшает усвоение железа. Пиридоксин снижает эффективность леводопы.

Условия хранения

  • хранить при комнатной температуре 15-25 градусов
  • беречь от детей
Отзывы Магнистад
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